Binzhang Shen

Massachusetts . Boston - United States

Binzhang Shen 的邮箱和电话

电子邮件 bsh***@***.com

Binzhang Shen 当前工作场所

Tango Therapeutics

Tango Therapeutics is a biotechnology company discovering and developing novel medicines targeting cancer vulnerabilities to deliver transformational new therapies for patients. Tango was launched in 2017 with a $55 million Series A investment from Third Rock Ventures. The company has established a robust product engine that leverages advances in DNA sequencing and CRISPR-based target discovery to generate breakthrough medicines that have the potential to provide deeper, more sustained benefit than today's targeted therapies, and extend the benefit of available immuno-oncology agents. Tango Therapeutics is focused on three areas of drug development, each in well-defined patient populations currently lacking effective treatment options, and each with hallmarks of cancer that have not been targeted yet. These include: loss of tumor suppressor gene function; multiple oncogenic drivers; and immune evasion. What fuels each of Tango's programs is an increasingly sophisticated ability to utilize synthetic lethality - the interaction between two genes that causes cell death when both are inactivated. In cancer cells, one of these genes is inactivated by mutation; the other will be inactivated by a drug. This approach leaves normal cells largely unaffected, with the potential to greatly enhance anti-tumor efficacy and reduce associated toxicity. Tango's success will be driven by its depth of understanding of the genetic subtypes of cancer, and corresponding insights into novel drug targets and combinations uniquely relevant to each subtype. By shaping discovery efforts in this way, Tango has the potential to reach the clinic quickly, and with a clear plan for identifying the patients most likely to benefit from each new treatment, an approach that could increase both speed and probability of success in translating novel target discoveries into transformational new medicines for patients.

Binzhang Shen 简介

公司 Tango Therapeutics
职位 Senior Principal Scientist
地点 United States
LinkedIn http://www.linkedin.com/in/binzhang-shen-55895b58
部门 master_engineering_technical
头衔 Molecular Biology

Binzhang Shen 的常见问题(FAQs)

Binzhang Shen 在哪家公司工作?

Binzhang Shen 在 Tango Therapeutics 担任 Molecular Biology

Binzhang Shen 在 Tango Therapeutics 的职位是什么?

Binzhang Shen 在 Tango Therapeutics 的职位是 Molecular Biology

Binzhang Shen 的电子邮件地址是什么?

Binzhang Shen 的电子邮件地址是 bsh***@***.com

Binzhang Shen 的电话号码是什么?

Binzhang Shen 的电话号码是 -

Binzhang Shen 的工作电话号码是什么?

Binzhang Shen 的公司电话号码是 +185****

Binzhang Shen 从事哪个行业?

Binzhang Shen 在 research 工作。

Binzhang Shen 的同事是谁?

Binzhang Shen 的一些同事包括Binzhang Shen、Colin Liang、Amanda Galgay、Jon ComeJade Green、。

我如何联系 Binzhang Shen?

Binzhang Shen联系方式: 电子邮件地址:bsh***@***.com 电话号码:-

Binzhang Shen 的个人领英是多少

Binzhang Shen 的个人领英是:http://www.linkedin.com/in/binzhang-shen-55895b58

Binzhang Shen 的办公地点在哪里?

Binzhang Shen 的办公地点:100 binney st, boston, massachusetts, united states

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